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The role concept (hereafter referred to as 'role') and corresponding ontological role model pattern provide a structured and modular way to capture many different real-world complexities.

Universal Statement (NO Role usage)

Example: Amlodipine

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Mesylate Monohydrate is included

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Amlodipine EMC (a pharmaceutical product)

Basic Role Pattern

In order to further specify a relationship we use the basic role pattern that allows to provide details that are valid only in a certain context.

Example: Amlodpine Besylate plays role active ingredient in Norvasc

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Drawio
border true diagramName Substance active ingredient role in included in product - Amlodipine mesylate monohydrate plays the active ingredient in Amlodipine EMC simpleViewer false width links auto tbstyle top lbox true diagramWidth 1041 revision 2

The important thing is that we can now attach all information that further specifies the role of Amlodipine mesylate monohydrate in the context of Amlodipine EMC to the middle role node in the graph. E.g., strength.

Roles and Constituents (Product Compositions)

substance constituency - constituency that defines some substance based on its relationship(s) to some other substance (ingredient) or moiety, potentially in some amount, in some context

More complex case where the constiuency of some substance or product is contingent on something, or for mixtures where there are amounts and other details in some contextwhere multiple roles need to be grouped and or distinguished in their representation, can be covered with the following constituency pattern.

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