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The example below explains how the GSRS Data on Amlodipine is represented in the structure of the IDMP Ontology.

Substance


Substance 
<https://spec.pistoiaalliance.org/idmp/ontology/ISO/ISO11238-Substances/ChemicalSubstance>
	rdf:type            owl:Class ; 
	rdfs:subClassOf     <https://spec.pistoiaalliance.org/idmp/ontology/ISO/ISO11238-Substances/SingleSubstance> ;        
    rdfs:label          "chemical substance" ;
    skos:definition	    "single substance that can be described as a stoichiometric or non-stoichiometric single molecular entity and is not a protein, nucleic acid or polymer substance" .

<https://spec.pistoiaalliance.org/idmp/ontology/ISO/ISO11238-Substances/SingleSubstance>
	rdf:type            owl:Class ; 
	rdfs:subClassOf		<https://spec.pistoiaalliance.org/idmp/ontology/ISO/ISO11238-Substances/Substance> ;        
	rdfs:label          “single substance" ;
	skos:definition	    "substance that can be described by a single representation or set of descriptive elements“ .

<https://spec.pistoiaalliance.org/idmp/ontology/ISO/ISO11238-Substances/Substance>
	rdf:type            owl:Class ;        
	rdfs:label          “single substance" ;
	skos:definition	    "substance that can be described by a single representation or set of descriptive elements“ .

<https://gsrs.ncats.nih.gov/api/v1/substances/1J444QC288>
	rdf:type            <https://spec.pistoiaalliance.org/idmp/ontology/ISO/ISO11238-Substances/ChemicalSubstance> ;        
	rdfs:label			"AMLODIPINE" .


Substance Names

Substance Names 
<https://gsrs.ncats.nih.gov/api/v1/substances/1J444QC288>
	rdf:type            	<https://spec.pistoiaalliance.org/idmp/ontology/ISO/ISO11238-Substances/ChemicalSubstance> ;        
	rdfs:label				"AMLODIPINE" ;
	cmns-dsg:hasName		<https://gsrs.ncats.nih.gov/api/v1/substances/1J444QC288/f7a0a700-a9e5-4be8-a615-7f4e271c8f00> .
	
<https://gsrs.ncats.nih.gov/api/v1/substances/1J444QC288/62fae2dd-eca3-4985-899b-79154991441a>
	rdf:type            	<https://spec.pistoiaalliance.org/idmp/ontology/ISO/ISO11238-Substances/SubstanceName> ;
	cmns-txt:hasTextValue	 "3-ETHYL 5-METHYL (+/-)-2-((2-AMINOETHOXY)METHYL)-4-(O-CHLOROPHENYL)-1,4-DIHYDRO-6-METHYL-3,5-PYRIDINEDICARBOXYLATE" ;
	cmns-cls:isClassifiedBy	 <https://spec.pistoiaalliance.org/idmp/ontology/ISO/ISO11238-RegistrationAuthorities/IUPACName> .
	
<https://spec.pistoiaalliance.org/idmp/ontology/ISO/ISO11238-Substances/SubstanceName>
	rdf:type            	owl:Class ; 
	rdfs:label 				"substance name" ;
	skos:definition			"name or company code associated with the substance" .
	
<https://spec.pistoiaalliance.org/idmp/ontology/ISO/ISO11238-RegistrationAuthorities/IUPACName>
	rdf:type				<https://spec.pistoiaalliance.org/idmp/ontology/ISO/ISO11238-Substances/SubstanceNameClassifier> ;
	rdfs:label 				"IUOPAC name" .
	
<https://spec.pistoiaalliance.org/idmp/ontology/ISO/ISO11238-Substances/SubstanceNameClassifier>
	rdf:type            	owl:Class ; 
	rdfs:label 				"substance name classifier" .



Substance Identifiers

Substance Identifiers 
<https://gsrs.ncats.nih.gov/api/v1/substances/1J444QC288>
	rdf:type            	<https://spec.pistoiaalliance.org/idmp/ontology/ISO/ISO11238-Substances/ChemicalSubstance> ;        
	rdfs:label				"AMLODIPINE" ;
	cmns-id:isIdentifiedBy <https://data.pistoiaalliance.org/EVMPD/SUB05467MIG> .
	
<https://data.pistoiaalliance.org/EVMPD/SUB05467MIG>
	rdf:type            				<https://spec.pistoiaalliance.org/idmp/ontology/ISO/ISO11238-RegistrationAuthorities/EudraVigilanceCode> ;        
	cmns-txt:hasTextValue				"SUB05467MIG" ;
	cmns-ra:isRegisteredIn				<https://spec.pistoiaalliance.org/idmp/ontology/ISO/ISO11238-RegistrationAuthorities/ExtendedEudraVigilanceMedicinalProductDictionary> ;
	cmns-ra:hasRegistrationAuthority	<https://spec.pistoiaalliance.org/idmp/ontology/ISO/ISO11238-RegistrationAuthorities/EuropeanMedicinesAgencyRegistrationAuthority> .

<https://spec.pistoiaalliance.org/idmp/ontology/ISO/ISO11238-RegistrationAuthorities/EudraVigilanceCode>
	rdfs:subClassOf     	owl:Class ;
	rdfs:subClassOf			<https://spec.pistoiaalliance.org/idmp/ontology/ISO/ISO11238-Substances/SubstanceCode> ;
	rdfs:label				"EudraVigilance code" ;
	cmns-av:abbreviation	"EV code" .

<https://spec.pistoiaalliance.org/idmp/ontology/ISO/ISO11238-Substances/SubstanceCode>
	rdf:type				owl:Class ;
	rdfs:subClassOf			<https://www.omg.org/spec/Commons/RegistrationAuthorities/RegisteredIdentifier> ;
	rdfs:label				"substance code" .

<https://www.omg.org/spec/Commons/RegistrationAuthorities/RegisteredIdentifier>
	rdf:type		   		owl:Class ;
	rdfs:label				"registered identifier" .

<https://spec.pistoiaalliance.org/idmp/ontology/ISO/ISO11238-RegistrationAuthorities/ExtendedEudraVigilanceMedicinalProductDictionary>
	rdf:type				<https://spec.pistoiaalliance.org/idmp/ontology/ISO/ISO11238-RegistrationAuthorities/Registry> ;
	rdfs:label				"eXtended EudraVigilance Medicinal Product Dictionary" ;
	cmns-av:abbreviation	"XEVMPD" .
	
<https://spec.pistoiaalliance.org/idmp/ontology/ISO/ISO11238-RegistrationAuthorities/Registry>
	rdf:type		     	owl:Class ;
	rdfs:label				"registry" .
	
<https://spec.pistoiaalliance.org/idmp/ontology/ISO/ISO11238-RegistrationAuthorities/EuropeanMedicinesAgencyRegistrationAuthority>
	rdf:type				<https://spec.pistoiaalliance.org/idmp/ontology/ISO/ISO11238-RegistrationAuthorities/RegistrationAuthority> ;
	rdfs:label				"European Medicines Agency Registration Authority" .
	
<https://spec.pistoiaalliance.org/idmp/ontology/ISO/ISO11238-RegistrationAuthorities/RegistrationAuthority>
	rdf:type		    	owl:Class ;
	rdfs:label				"registration authority" .


Substance Codes

clearly describe difference to "Substance Identifiers"








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