Business' relevance

A medicinal product can contain a mixture of substances of which each can have different functions (active ingredient, inactive ingredient, adjuvant). It is the active ingredient in a medicinal product which is responsible for the pharmacological activity of the medical product. In turn, the active moiety refers to the part of the active ingredient which exerts the pharmacological action of the substance. This can consist of only a part of or the entire molecule of the substance that is designated as the active ingredient. Since an active moiety can exist in different forms in different substances, it would be useful to be able to identify the possible substances which have a certain common active moiety. This unambiguous identification of substances and active moieties will enable a clear oversight of the involved substance identifiers.

Diagram for Query Pattern

Diagram 1: Query pattern diagram for SPARQL Query

Test data

Amlodipine example: https://github.com/edmcouncil/idmp/blob/master/EXT/Examples/AmlodipineExample.rdf

Terlipressin Example: https://github.com/edmcouncil/idmp/blob/master/EXT/Examples/TerlipressinExample.rdf

Query

https://github.com/edmcouncil/idmp/blob/master/etc/CQ/Example/uc1_cq1.sparql

Expected Query Result for Amlodipine Example Data

Open

Expected Query Result for Terlipressin Example Data

Open